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Article

SLCO1B1 Polymorphisms and Statin-Induced Myopathy

1 Jan 2013

Abstract excerpt

Statin drugs are highly effective in lowering blood concentrations of LDL-cholesterol, with concomitant reduction in risk of major cardiovascular events. Although statins are generally regarded as safe and well-tolerated, some users develop muscle symptoms that are mostly mild but in rare cases can lead to life-threatening rhabdomyolysis. The SEARCH genome-wide association study, which has been independently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24459608
DOI: 10.1371/currents.eogt.d21e7f0c58463571bb0d9d3a19b82203

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