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Article

Genetic Determinants of Statin-induced Myopathy: A Network Meta-analysis of Observational Studies.

Current reviews in clinical and experimental pharmacology - 1 Jan 2026

Sridharan Kannan, Sivaramakrishnan Gowri

Abstract excerpt

INTRODUCTION: Statin-induced myopathy (SIM) is a prevalent adverse event impacting treatment adherence. Despite extensive exploration of single nucleotide polymorphisms (SNPs), conflicting evidence obscures their role in SIM incidence, prompting this network meta-analysis. METHODS: Observational studies meeting eligibility criteria (patients on any statin with reported SNPs and SIM details) were systematically...

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Source

Identifiers

PMID: 40176697
DOI: 10.2174/0127724328356429250315163111

Genes

SLCO1B1
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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