Article

Neural mass modelling reveals that hyperexcitability underpins slow-wave sleep changes in children with epilepsy

2024-07-15

Abstract excerpt

<h4>Objective</h4> The relationship between sleep and epilepsy is important but imperfectly understood. We sought to understand why children with epilepsy have altered sleep homeostasis. <h4>Methods</h4> We used neural mass models to replicate sleep EEG recorded from 15 children with focal lesional epilepsies and 16 healthy age-matched controls. <h4>Results</h4> The models revealed that sleep EEG differences are d...

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Literature Corpus work: fb176289-e351-517b-96d8-6c591d9bc035
DOI: 10.1101/2024.07.15.24310128

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