Article

Sequence based prediction of cell type specific microRNA binding and mRNA degradation for therapeutic discovery

2025-05-16

Abstract excerpt

MicroRNAs and RNA binding proteins are crucial elements of post-transcriptional gene regulation, which governs the fate of mRNA molecules in the cell. However, the landscape of these regulatory interactions, particularly across different mammalian cell types, remains underexplored. We describe REPRESS, a deep learning model that predicts cell-type-specific microRNA binding and mRNA degradation directly from RNA se...

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Identifiers and source

Literature Corpus work: 7267ce19-d84a-552d-a52a-488dc0671421
DOI: 10.1101/2025.05.15.654105

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