Article

Single-molecule long-read sequencing reveals a conserved selection mechanism determining intact long RNA and miRNA profiles in sperm

2020-05-30

Abstract excerpt

Sperm contributes diverse RNAs to the zygote. While sperm small RNAs have been shown to be shaped by paternal environments and impact offspring phenotypes, we know little about long RNAs in sperm, including mRNAs and long non-coding RNAs. Here, by integrating PacBio single-molecule long reads with Illumina short reads, we found 2,778 sperm intact long transcript (SpILT) species in mouse. The SpILTs profile is evol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7255bbde-c468-53be-a5de-c9f2d7da7e5f
DOI: 10.1101/2020.05.28.122382

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-molecule long-read sequencing reveals a conserved selection mechanism determining intact long RNA and miRNA profiles in spermDOI 10.1101/2020.05.28.122382Read

A comprehensive overview of bull sperm-borne small non-coding RNAs and their diversity across breeds.Semantic proximity Read

Paternal Contributions to Offspring Health: Role of Sperm Small RNAs in Intergenerational Transmission of Epigenetic InformationSemantic proximity Read

Role of small RNAs harbored by sperm in embryonic development and offspring phenotype.Semantic proximity Read

The composition of human sperm sncRNAome: a cross-country small RNA profilingSemantic proximity Read

The ENCODE4 long-read RNA-seq collection reveals distinct classes of transcript structure diversitySemantic proximity Read

Long- and short-read RNA sequencing from five reproductive organs of boar.Semantic proximity Read

Stallion Sperm Transcriptome Comprises Functionally Coherent Coding and Regulatory RNAs as Revealed by Microarray Analysis and RNA-seqSemantic proximity Read

All you need to know about sperm RNAsSemantic proximity Read

Maternal factor PABPN1L is essential for maternal mRNA degradation during maternal-to-zygotic transitionSemantic proximity Read

Single-Cell RNA Sequencing of Human, Macaque, and Mouse Testes Uncovers Conserved and Divergent Features of Mammalian SpermatogenesisSemantic proximity Read

Dissecting Small Noncoding RNA Landscapes in Mouse Preimplantation Embryos and Human Blastoids for Modeling Early Human EmbryogenesisSemantic proximity Read

Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization.Semantic proximity Read