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All you need to know about sperm RNAs

9 Sept 2021

Abstract excerpt

BACKGROUND: Spermatogenesis generates a small and highly specialised type of cell that is apparently incapable of transcription and translation. For many years, this dogma was supported by the assumption that (i) the compact sperm nucleus, resulting from the substitution of histones by protamine during spermatogenesis, renders the genome inaccessible to the transcriptional machinery; and (ii) the loss of most...

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PMID: 34624094
DOI: 10.1093/humupd/dmab034

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