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The composition of human sperm sncRNAome: a cross-country small RNA profiling

6 Mar 2025

Abstract excerpt

BACKGROUND: Over the last decade, numerous studies have implicated sperm-borne small non-coding RNAs (sncRNAs) in fertility and transgenerational inheritance. Spermatozoa contain a variety of small RNAs; however, inter-individual and inter-population variations in the human sperm sncRNA content (sncRNAome) have not yet been ascertained. METHODS: We performed sncRNA sequencing in 54 normozoospermic proven fertile...

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PMID: 40050854
DOI: 10.1186/s12958-025-01358-3

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