Article

MicroRNA miR-1002 enhances NMNAT-mediated stress response by modulating alternative splicing

2019-05-17

Abstract excerpt

<h4>SUMMARY</h4> Understanding endogenous regulation of stress resistance and homeostasis maintenance is critical to developing neuroprotective therapies. Nicotinamide mononucleotide adenylyltransferase (NMNAT) is a conserved essential enzyme that confers extraordinary protection and stress resistance in many neurodegenerative disease models. Drosophila Nmnat is alternatively spliced to two mRNA variants, RA and...

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Literature Corpus work: 72180560-9153-58f5-bcdf-fc0bcb9a2af5
DOI: 10.1101/641944

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