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Article

Hsrω and Other lncRNAs in Neuronal Functions and Disorders in Drosophila

21 Dec 2022

Abstract excerpt

Long noncoding RNAs (lncRNAs) have a crucial role in epigenetic, transcriptional and posttranscriptional regulation of gene expression. Many of these regulatory lncRNAs, such as MALAT1, NEAT1, HOTAIR, etc., are associated with different neurodegenerative diseases in humans. The lncRNAs produced by the hsrω gene are known to modulate neurotoxicity in polyQ and amyotrophic lateral sclerosis disease models of...

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PMID: 36675966
DOI: 10.3390/life13010017

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