Article

Single-Cell Analysis Reveals Ide-cel and Cilta-cel Characteristics That Influence Efficacy

2024-10-11

Abstract excerpt

<title>Abstract</title><p>Chimeric antigen receptor T-cells targeting BCMA have revolutionized the treatment of relapsed/refractory multiple myeloma (RRMM) with two approved products, idecabtagene vicleucel (ide-cel) and ciltacabtagene autoleucel (cilta-cel). To explore biological differences, we analyzed pre-infusion products (IP) and CAR-enriched peripheral blood mononuclear cells (PBMCs) at expansion using sing...

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Literature Corpus work: 71f0f74f-b900-5328-a13b-3d35ad815340
DOI: 10.21203/rs.3.rs-4994668/v1

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