Article

DHRS7 Integrates NADP <sup>+</sup> /NADPH Redox Sensing with Inflammatory Lipid Signalling via the Oxoeicosanoid Pathway

2025-02-08

Abstract excerpt

During the innate immune response at epithelial wound sites, oxidative stress acts microbicidal and—mechanistically less well understood—as an immune and resilience signal. The reversible sulfhydryl (SH) oxidation of kinases, phosphatases, and transcription factors constitute the perhaps best-known redox signalling paradigm, whereas mechanisms that transduce metabolic redox cues, such as redox cofactor balance, re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 71d641d2-fbc9-5da3-9394-73011d396b72
DOI: 10.1101/2025.02.05.636725

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

DHRS7 Integrates NADP <sup>+</sup> /NADPH Redox Sensing with Inflammatory Lipid Signalling via the Oxoeicosanoid PathwayDOI 10.1101/2025.02.05.636725Read

5,6-Epoxycholestanols Metabolism and Functions: Defining the Epoxycholestanoid (EChA) FamilySemantic proximity Read

The G-protein coupled receptor OXER1 is a tissue redox sensor essential for intestinal epithelial barrier integritySemantic proximity Read

PRDX4, an endoplasmic reticulum-localized peroxiredoxin at the crossroads between enzymatic oxidative protein folding and nonenzymatic protein oxidation.Semantic proximity Read

Thiol redox systems and protein kinases in hepatic stellate cell regulatory processes.Semantic proximity Read

Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways.Semantic proximity Read

Myeloid DRP1 Sulfenylation Drives Reparative Macrophage Polarization and Neovascularization in Ischemic MuscleSemantic proximity Read

Unveiling Immune System Perturbations in Early Development Through Zebrafish Models of NADHX Repair Deficiency.Semantic proximity Read

Effects of A2E-Induced Oxidative Stress on Retinal Epithelial Cells: New Insights on Differential Gene Response and Retinal DystrophiesSemantic proximity Read

COVID-19: A Redox Disease—What a Stress Pandemic Can Teach Us About Resilience and What We May Learn from the Reactive Species Interactome About Its TreatmentSemantic proximity Read

Glutathionylation of Pyruvate Dehydrogenase Complex E2 and Inflammatory Cytokine Production During Acute Inflammation Are Magnified By Mitochondrial Oxidative StressSemantic proximity Read

Redox Signaling of NADPH Oxidases Regulates Oxidative Stress Responses, Immunity, and AgingSemantic proximity Read

Literature-Based Enrichment Insights into Redox Control of Vascular BiologySemantic proximity Read