Article

Small molecule binding to disordered proteins

2020-01-01

Abstract excerpt

The human proteome includes many proteins that are entirely disordered or contain long disordered regions. Although these proteins are linked with many diseases, there are currently no clinically-approved drugs that have been shown to target these proteins in their monomeric forms. In fact, disordered proteins are generally considered to be 'untargettable'. This situation has arisen from a lack of understanding of...

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Identifiers and source

Literature Corpus work: 71c4e645-387e-5ec4-ba71-cb8ec8317214
DOI: 10.17863/cam.50089

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