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Energy Conservation Drives Adaptive Specialization Through Fine-tuned Organizations

2025-12-10

Abstract excerpt

Energy conservation is at the basis of evolutionary optimization in living systems. Yet, how cells maintain function during metabolic stress while preserving adaptive capacity remains unclear. Here, we use a functional genomics approach to identify metabolic human accelerated regions (mHARs) genomic hubs (evolutionarily tuned regions) in adipose tissue that coordinate adaptive responses to nutrient deficit. During...

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Literature Corpus work
7174c1ac-c7e3-5104-87f2-9c2bfab08881
DOI
10.64898/2025.12.06.692764
Open publication

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Energy Conservation Drives Adaptive Specialization Through Fine-tuned OrganizationsDOI 10.64898/2025.12.06.692764
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