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Macrophage heterogeneity and plasticity in tuberculosis

2 Apr 2019

Abstract excerpt

Macrophages are the primary host cells for Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), during its intracellular survival in humans. The pathogen has a remarkable capacity to survive within the hostile environment of macrophages. However, primary infection does not result in active TB disease in most individuals. The majority of individuals remain latently infected, wherein the bacteria...

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PMID: 30938876
DOI: 10.1002/jlb.mr0318-095rr

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