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From infection niche to therapeutic target: the intracellular lifestyle of Mycobacterium tuberculosis

7 Apr 2021

Abstract excerpt

(Mtb) is an obligate human pathogen killing millions of people annually. Treatment for tuberculosis is lengthy and complicated, involving multiple drugs and often resulting in serious side effects and non-compliance. Mtb has developed numerous complex mechanisms enabling it to not only survive but replicate inside professional phagocytes. These mechanisms include, among others, overcoming the phagosome maturation...

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PMID: 33826491
DOI: 10.1099/mic.0.001041

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