Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Macrophage Differentiation and Metabolic Adaptation in Mycobacterial Infections

27 Feb 2025

Abstract excerpt

The adaptation of macrophages—the most common tissue-resident immune cells—to metabolic and microbial cues with high local variability is essential for the maintenance of organ integrity. In homeostasis, macrophages show largely predictable tissue-specific differentiation, as recently revealed by multidimensional methods. However, chronic infections with human-adapted pathogens substantially contribute to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to Mycobacterium research and diagnosis
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40014665
DOI: 10.1146/annurev-immunol-082323-120757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Macrophage Differentiation and Metabolic Adaptation in Mycobacterial InfectionsPMID 40014665Read ↗

Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases.Semantic proximity Read ↗

<i>Mycobacterium tuberculosis</i> diversity and macrophage heterogeneity dictate phagosomal acidificationSemantic proximity Read ↗

Macrophage heterogeneity and plasticity in tuberculosisSemantic proximity Read ↗

Mycobacterial infection uncovers plasticity of Kupffer cellsSemantic proximity Read ↗

Systems analysis reveals alternate metabolic states adopted by <i>Mycobacterium tuberculosis</i> across speciesSemantic proximity Read ↗

Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human DiseasesSemantic proximity Read ↗

Macrophage: A Cell With Many Faces and Functions in TuberculosisSemantic proximity Read ↗

The evolutionary tug-of-war of macrophage metabolism during bacterial infection.Semantic proximity Read ↗

Macrophage polarization: convergence point targeted by Mycobacterium tuberculosis and HIVSemantic proximity Read ↗

The many niches and strategies used by pathogenic mycobacteria for survival within host macrophagesSemantic proximity Read ↗

Macrophage Heterogeneity in the Immunopathogenesis of TuberculosisSemantic proximity Read ↗

Cross-Kingdom Infection of Macrophages Reveals Pathogen- and Immune-Specific Global Reprogramming and AdaptationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.