Article

MeDUsA: A novel system for automated axon quantification to evaluate neuroaxonal degeneration

2021-10-26

Abstract excerpt

<h4>Background</h4> Drosophila is an excellent model organism for studying human neurodegenerative diseases (NDs), and the rough eye phenotype (REP) assay is a convenient experimental system for analysing the toxicity of ectopically expressed human disease genes. However, the association between REP and axonal degeneration, an early sign of ND, remains unclear. To address this question, we developed a method to e...

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Literature Corpus work: 70dfd2a0-e7a5-52d4-a948-58a0d620f88e
DOI: 10.1101/2021.10.25.465674

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