Article

NMJ-Analyser: high-throughput morphological screening of neuromuscular junctions identifies subtle changes in mouse neuromuscular disease models

2020-09-25

Abstract excerpt

The neuromuscular junction (NMJ) is the peripheral synapse formed between a motor neuron axon terminal and a muscle fibre. NMJs are thought to be the primary site of peripheral pathology in many neuromuscular diseases, but innervation/denervation status is often assessed qualitatively with poor systematic criteria across studies, and separately from 3D morphological structure. Here, we describe the development of...

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Literature Corpus work: 7c30cb3f-6ae8-5b5f-8d3f-49c680678d7b
DOI: 10.1101/2020.09.24.293886

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