Article

A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway

2020-11-24

Abstract excerpt

<h4>Background: </h4> Anti-angiogenic therapy has been widely applied to the clinical treatment of malignant tumors. However, the efficacy of such treatments has been called into question, especially in triple-negative breast cancer (TNBC). Bevacizumab, the first anti-angiogenic agent approved by FDA, actually increases invasive and metastatic properties of TNBC cells, resulting from the activation of Wnt/β-cateni...

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Literature Corpus work: 70c0eff8-b641-57b2-8d7c-9919b2aa1e53
DOI: 10.21203/rs.3.rs-66233/v2

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