Article
Anti-angiogenesis therapy in cancer: current challenges and future perspectives.
Cancer letters - 28 Jul 2012
Shojaei Farbod
Abstract excerpt
It has been nearly 9years since the FDA (Food and Drug Administration) approved the first anti-angiogenic drug (bevacizumab) for treatment of metastatic colorectal cancer. Other angiogenic inhibitors have since been approved or are in different stages of clinical trials. However, continued clinical and preclinical investigations have identified major drawbacks associated with the application of this class of...
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