Article
Development of a Recombinant Monospecific Anti-PLGF Bivalent Nanobody and Evaluation of it in Angiogenesis Modulation.
Molecular biotechnology - 1 Dec 2020
Nikooharf Abolfazl, Arezumand Roghaye, Mansouri Kamran, Khoshi Amir Hossein, Namdar Ahmadabad Hassan
Abstract excerpt
During the past two decades, tumor therapy based on monoclonal antibody has been found as a confident therapeutic approach in solid tumors and hematologic malignancies. Nanobodies are the smallest fragment of an antigen-binding domain in heavy chain-only antibody originated from the Camelidae family. Accordingly, they are being recently developed rapidly as diagnostic and therapeutic agents. In this regard,...
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