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Article

Inhibition of FGF-FGFR and VEGF-VEGFR signalling in cancer treatment.

Cell proliferation - 1 Apr 2021

Liu Guihong, Chen Tao, Ding Zhenyu, Wang Yang, Wei Yuquan, Wei Xiawei

Abstract excerpt

The sites of targeted therapy are limited and need to be expanded. The FGF-FGFR signalling plays pivotal roles in the oncogenic process, and FGF/FGFR inhibitors are a promising method to treat FGFR-altered tumours. The VEGF-VEGFR signalling is the most crucial pathway to induce angiogenesis, and inhibiting this cascade has already got success in treating tumours. While both their efficacy and antitumour spectrum...

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Identifiers

PMID: 33655556
DOI: 10.1111/cpr.13009
PMCID: PMC8016646

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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