Article

Complementing Muscle Regeneration: Fibro-Adipogenic Progenitor and Macrophage-Mediated Repair of Elderly Human Skeletal Muscle

2024-04-18

Abstract excerpt

The capacity to regenerate skeletal muscle function after injury requires a complex and well-coordinated cellular response. Here, we unravel the intricate dynamics of human skeletal muscle regeneration by combining spatial, temporal, and single cell transcriptomics. Using spatial RNA sequencing, we profiled the expression of human protein-coding genes in elderly human skeletal muscle biopsies before as well as 2-,...

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Literature Corpus work: 709c8ff5-9a11-532d-bf20-fd9d1863cdd3
DOI: 10.1101/2024.04.18.590053

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