Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Growth Inhibition by Testosterone in an Androgen Receptor Splice Variant-Driven Prostate Cancer Model.

The Prostate - 1 Dec 2016

Nakata Daisuke, Nakayama Kazuhide, Masaki Tsuneo, Tanaka Akira, Kusaka Masami, Watanabe Tatsuya

Abstract excerpt

BACKGROUND: Castration resistance creates a significant problem in the treatment of prostate cancer. Constitutively active splice variants of androgen receptor (AR) have emerged as drivers for resistance to androgen deprivation therapy, including the next-generation androgen-AR axis inhibitors abiraterone and enzalutamide. In this study, we describe the characteristics of a novel castration-resistant prostate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Androgen Receptor Antagonists
Share to Heterografts

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neoplasm Transplantation

Share to Orchiectomy

Share to Prostate-Specific Antigen

Share to Prostatic Neoplasms, Castration-Resistant

Share to Receptors, Androgen

Share to Testosterone

Source

Identifiers

PMID: 27473672
DOI: 10.1002/pros.23238

Genes

KLK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Growth Inhibition by Testosterone in an Androgen Receptor Splice Variant-Driven Prostate Cancer Model.PMID 27473672Read ↗

Biologic and clinical significance of androgen receptor variants in castration resistant prostate cancer.Semantic proximity Read ↗

Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical ApplicationsSemantic proximity Read ↗

Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting.Semantic proximity Read ↗

Constitutive activity of the androgen receptor.Semantic proximity Read ↗

Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate CancerSemantic proximity Read ↗

Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptorSemantic proximity Read ↗

Experimental Evidence of Persistent Androgen-Receptor-Dependency in Castration-Resistant Prostate CancerSemantic proximity Read ↗

Androgen receptor signaling and mutations in prostate cancer.Semantic proximity Read ↗

Androgen receptor: past, present and future.Semantic proximity Read ↗

[Molecular biology of castration-resistant prostate cancer].Semantic proximity Read ↗

Androgen receptor (AR) heterogeneity in prostate cancer and therapy resistanceSemantic proximity Read ↗

Loss and revival of androgen receptor signaling in advanced prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.