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Article

Supplemental cellular protection by a carotenoid extends lifespan via Ins/IGF-1 signaling in Caenorhabditis elegans.

Oxidative medicine and cellular longevity - 1 Jan 2011

Yazaki Koumei, Yoshikoshi Chinatsu, Oshiro Satoru, Yanase Sumino

Abstract excerpt

Astaxanthin (AX), which is produced by some marine animals, is a type of carotenoid that has antioxidative properties. In this study, we initially examined the effects of AX on the aging of a model organism C. elegans that has the conserved intracellular pathways related to mammalian longevity. The continuous treatments with AX (0.1 to 1 mM) from both the prereproductive and young adult stages extended the mean...

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Identifiers

PMID: 22013497
DOI: 10.1155/2011/596240
PMCID: PMC3195502

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