Article

Extracellular vesicles derived from induced pluripotent stem cells mediate anti- inflammatory effects in primary human macrophages

2025-08-29

Abstract excerpt

<title>Abstract</title> <p> Extracellular vesicles derived from induced pluripotent stem cells (iPSC EVs) have immunoregulatory potential with the ability to alter the macrophage phenotype. Modulating the macrophage phenotype towards an anti-inflammatory, pro-resolving state may be beneficial in the treatment of chronic inflammatory diseases. The contents of iPSC EVs and their effects on macrophages are poorly u...

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Literature Corpus work: 703eda22-fd7b-58d6-aa50-63c73c01c869
DOI: 10.21203/rs.3.rs-7436803/v1

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