Article

Family-Wide Photoproximity Profiling of Integrin Protein Social Networks in Cancer

2024-09-22

Abstract excerpt

Integrin family transmembrane receptors mediate dynamic interactions between cells and their extracellular microenvironment. The heterogeneous interaction partners of integrins directly regulate cell adhesion, motility, proliferation, and intracellular signaling. Despite the recognized importance of protein-protein interactions and the formation of signaling hubs around integrins, the ability to detect and quantif...

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Identifiers and source

Literature Corpus work: 6ff8a329-561c-5907-8756-3893b1d25484
DOI: 10.1101/2024.09.18.613588

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