Article

Comprehensive characterization of the integrin family across 32 cancer types

2023-12-24

Abstract excerpt

<h4>ABSTRACT</h4> Integrin genes widely involve in tumorigenesis. Yet, a comprehensive characterization of integrin family and their interactome on the pan-cancer level is lacking. Here, we systematically dissect integrin family in nearly 10000 tumors across 32 cancer types. Globally, integrins represent a frequently altered and misexpressed pathway, with alteration and dysregulation overall being protumorigenic....

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Literature Corpus work: d8239eab-6281-5fd3-80ea-23d7dcae037b
DOI: 10.1101/2023.12.24.573245

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