Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive Characterization of the Integrin Family Across 32 Cancer Types

9 May 2024

Abstract excerpt

Integrin genes are widely involved in tumorigenesis. Yet, a comprehensive characterization of integrin family members and their interactome at the pan-cancer level is lacking. Here, we systematically analyzed integrin family in approximately 10,000 tumors across 32 cancer types. Globally, integrins represent a frequently altered and misexpressed pathway, with alteration and dysregulation overall being...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Cell Adhesion Molecules Research
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39436262
DOI: 10.1093/gpbjnl/qzae035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Characterization of the Integrin Family Across 32 Cancer TypesPMID 39436262Read ↗

Comprehensive characterization of the integrin family across 32 cancer typesSemantic proximity Read ↗

Integrin signaling in tumor biology: mechanisms of intercellular crosstalk and emerging targeted therapiesSemantic proximity Read ↗

Integrins Within the Tumor Microenvironment: Biological Functions and Advances in Therapeutic Targeting <strong> </strong>Semantic proximity Read ↗

Integrins regulate stemness in solid tumor: an emerging therapeutic target.Semantic proximity Read ↗

Integrated Analysis of Prognostic and Immune Associated Integrin Family in Ovarian CancerSemantic proximity Read ↗

Integrins and cancer.Semantic proximity Read ↗

Molecular typing of gliomas on the basis of integrin family genes and a functional study of ITGA7Semantic proximity Read ↗

Lung adenocarcinoma-specific three-integrin signature contributes to poor outcomes by metastasis and immune escape pathwaysSemantic proximity Read ↗

A Pan-Cancer Analysis of the Oncogenic Role of Integrin Beta4 (ITGB4) in Human TumorsSemantic proximity Read ↗

A Machine Learning-Based Investigation of Integrin Expression Patterns in Cancer and MetastasisSemantic proximity Read ↗

Establishment of a novel prognostic signature based on an identified expression profile of integrin superfamily to predict overall survival of patients with colorectal adenocarcinomaSemantic proximity Read ↗

A Bioinformatic Investigation into the Role of ITGB1 in Cancer Prognosis and Therapeutic ResistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.