Article

<i>Snord116</i> -dependent diurnal rhythm of DNA methylation in mouse cortex

2017-09-05

Abstract excerpt

Rhythmic oscillations of physiological processes depend on integrating the circadian clock and diurnal environment. DNA methylation is epigenetically responsive to daily rhythms, as a subset of CpG dinucleotides in brain exhibit diurnal rhythmic methylation. A major genetic effect on rhythmic methylation was identified in a mouse Snordll6 deletion model of the imprinted disorder Prader-Willi syndrome (PWS). Of th...

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Literature Corpus work: 6ff41492-6acc-5807-acfb-1b2094fc935e
DOI: 10.1101/184788

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