Article

Targeting PHB1 to inhibit castration-resistant prostate cancer progression in vitro and in vivo

2022-12-07

Abstract excerpt

<title>Abstract</title> <p>Background Castration-resistant prostate cancer (CRPC) is currently the main challenge for prostate cancer (PCa) treatment, and there is an urgent need to find novel therapeutic targets and drugs. Prohibitin (PHB1) is a multifunctional chaperone/scaffold protein that is upregulated in various cancers and plays a pro-cancer role. FL3 is a synthetic flavagline drug that inhibits cancer c...

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Literature Corpus work: 1cd53b2f-5706-5993-b551-81db438767b7
DOI: 10.21203/rs.3.rs-2325130/v1

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