Article

Gene expression heterogeneity during brain development and aging: temporal changes and functional consequences

2019-04-01

Abstract excerpt

Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased variability between cells and individuals over time. Although increased inter-individual heterogeneity in gene expression was previously reported, whether this process starts during development or if it is restricted to the aging period has not yet been studied. The regulatory dynamics...

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Literature Corpus work: 6faabf0c-8d42-58f5-a2c8-4db5edee94c8
DOI: 10.1101/595249

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