Article

Aging shapes the population-mean and ‐dispersion of gene expression in human brains

2016-02-17

Abstract excerpt

Human aging is associated with cognitive decline and an increased risk of neurodegenerative disease. Our objective for this study was to evaluate potential relationships between age and variation in gene expression across different regions of the brain. We analyzed the Genotype-Tissue Expression (GTEx) data from 54 and 101 tissue samples across 13 brain regions in post-mortem donors of European descent aged betwee...

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Literature Corpus work: 52c98317-2308-5e07-bf7e-cdebeb4cb30c
DOI: 10.1101/039933

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