Article
Surface Modification of Biodegradable Microparticles With the Novel Host-Derived Immunostimulant CPDI-02 Significantly Increases Short-Term and Long-Term Mucosal and Systemic Antibodies Against Encapsulated Protein Antigen in Young Naïve Mice After Respi
2022-08-08
Abstract excerpt
Generating long-lived mucosal and systemic antibodies through respiratory immunization with protective antigens encapsulated in nanoscale biodegradable particles could potentially decrease or eliminate the incidence of many infectious diseases but requires incorporation of a suitable mucosal immunostimulant. We previously found that respiratory immunization with a model protein antigen (LPS-free OVA) encapsulated...
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Identifiers and source
- Literature Corpus work
- 6f886e04-4c50-51ec-82e2-92ff292fa119
- DOI
- 10.20944/preprints202208.0144.v1
