Article

Lenvatinib Inhibits Intrahepatic Cholangiocarcinoma Growth via Gadd45a-Mediated Cell Cycle Arrest

2021-09-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Intrahepatic cholangiocarcinoma (ICC) is the second most common primary liver cancer, and its 5-year survival rate is less than 10%. Fibroblast growth factor receptor (FGFR) changes have been observed in 6%-50% of ICC patients, and patients with FGFR mutations have been shown to have more inert tumour biological activity than patients with wild-type FGFRs. Thus,...

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Literature Corpus work: 6f72463a-a6e3-5504-a425-9410dc98522a
DOI: 10.21203/rs.3.rs-885590/v1

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