Article

Characterization of Viral Insulins Reveals White Adipose Tissue Specific Effects in Mice

2020-08-22

Abstract excerpt

<h4>ABSTRACT</h4> Members of the insulin/IGF superfamily are well conserved across the evolutionary tree. We recently showed that four viruses in the Iridoviridae family possess genes that encode proteins highly homologous to human insulin/IGF-1. Using chemically synthesized single chain (sc), i.e. IGF-1-like, forms of the viral insulin/IGF-1 like peptides (VILPs), we previously showed that they can stimulate hu...

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Identifiers and source

Literature Corpus work: 6f56c8d6-a555-5e6c-8d7d-039cd54a7c11
DOI: 10.1101/2020.08.21.261321

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