Article

High Affinity Nanobodies Block SARS-CoV-2 Spike Receptor Binding Domain Interaction with Human Angiotensin Converting Enzyme

2020-07-24

Abstract excerpt

<h4>ABSTRACT</h4> There are currently no approved effective treatments for SARS-CoV-2, the virus responsible for the COVID-19 pandemic. Nanobodies are 12-15 kDa single-domain antibody fragments that are amenable to inexpensive large-scale production and can be delivered by inhalation. We have isolated nanobodies that bind to the SARS-CoV-2 spike protein receptor binding domain and block spike protein interaction...

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Literature Corpus work: 6f394706-e794-570e-b293-bef4686a686b
DOI: 10.1101/2020.07.24.219857

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High Affinity Nanobodies Block SARS-CoV-2 Spike Receptor Binding Domain Interaction with Human Angiotensin Converting EnzymeDOI 10.1101/2020.07.24.219857Read

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