Article

Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent MS risk

2020-04-29

Abstract excerpt

<h4>Background</h4> The mechanisms linking UV radiation and vitamin D exposure to the risk of acquiring the latitude and critical period dependent autoimmune disease, multiple sclerosis, is unclear. We examined the effect of vitamin D on DNA methylation as well as DNA methylation at vitamin D receptor binding sites in adult and paediatric myeloid cells. <h4>Results</h4> Very few DNA methylation changes occurred...

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Literature Corpus work: 6f32cd55-2faa-5fdc-bc7f-8f6f258a31c3
DOI: 10.1101/2020.04.27.062075

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