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Article

Methylation of the Vitamin D Receptor Gene in Human Disorders

20 Dec 2023

Abstract excerpt

The Vitamin D Receptor (VDR) mediates the actions of 1,25-Dihydroxvitamin D3 (1,25(OH)2D3), which has important roles in bone homeostasis, growth/differentiation of cells, immune functions, and reduction of inflammation. Emerging evidences suggest that epigenetic modifications of the VDR gene, particularly DNA methylation, may contribute to the onset and progression of many human disorders. This review aims to...

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PMID: 38203278
DOI: 10.3390/ijms25010107

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