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Article

Lymphoid-tissue-on-chip recapitulates human antibody responses in vitro

2025-01-18

Abstract excerpt

<h4>ABSTRACT</h4> In the past decades, vaccine development has made great strides. Nevertheless, more often than not, vaccine candidates fail in advanced stages of development and clinical trials. A key reason is the poor predictive value of non-clinical in vivo and in vitro models, due to either species-specific differences in the immune response or insufficient reflection of physiological vaccine mechanisms. Re...

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Literature Corpus work
6f285dbd-31d7-50cb-9409-4648857d1dfa
DOI
10.1101/2025.01.14.632762
Open publication

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Lymphoid-tissue-on-chip recapitulates human antibody responses in vitroDOI 10.1101/2025.01.14.632762
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