Article

<i>VGLL2-NCOA2</i> leverages developmental programs for pediatric sarcomagenesis

2021-09-16

Abstract excerpt

Clinical sequencing efforts are uncovering numerous fusion genes in childhood solid tumors, yet few methods exist to delineate fusion-oncogenes from structural changes of unknown significance. One such novel fusion gene is VGLL2-NCOA2 , which was described by us and others in patients with congenital sarcomas but has lacked functional validation. To determine if this fusion is an oncogene, and how it is driving d...

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Literature Corpus work: 6f132baf-abff-54b8-a658-134135eda4e6
DOI: 10.1101/2021.09.15.460544

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