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Fusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma

31 Oct 2016

Abstract excerpt

Gene fusions and fusion products were thought to be unique features of neoplasia. However, more and more studies have identified fusion RNAs in normal physiology. Through RNA sequencing of 27 human noncancer tissues, a large number of fusion RNAs were found. By analyzing fusion transcriptome, we observed close clusterings between samples of same or similar tissues, supporting the feasibility of using fusion RNA...

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PMID: 27799565
DOI: 10.1073/pnas.1612734113

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