Article

Exact-match search with functional variant prediction enables automated DNA screening

2024-04-02

Abstract excerpt

Custom DNA synthesis underpins modern biology, but controlled genes in the wrong hands could threaten many lives and public trust in science. In .1992, a virology-trained mass murderer tried and failed to obtain physical samples of Ebola; today, viruses can be assembled from synthetic DNA fragments. Screening orders for controlled sequences is unreliable and expensive because current similarity search algorithms y...

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Literature Corpus work: 6ed8485e-e4d6-5054-8064-e673c471f31b
DOI: 10.1101/2024.03.20.585782

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