Article
Chemical biology of DNA polymerases: from selectivity to new functions.
Nucleic acids symposium series (2004) - 1 Jan 2007
Marx Andreas, Summerer Daniel, Sauter Katharina B M, Gloeckner Christian, Rudinger Nicolas Z
Abstract excerpt
DNA polymerases are involved in all DNA synthesis occurring in nature. Furthermore, DNA polymerases are the workhorses in numerous important molecular biological core technologies like the ubiquitous polymerase chain reaction (PCR), cDNA cloning, genome sequencing and nucleic acids based diagnostics. In order to identify DNA polymerase mutants with altered properties, we set up an efficient high through put setup...
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