Article

Cell fusion reprograms tumor cells and promotes RUNX1-mediated invasion and dissemination in colorectal cancer

2026-04-15

Abstract excerpt

<h4>Summary</h4> Metastasis remains the primary cause of cancer-related morbidity and mortality, despite significant advances in targeted therapies. Although metastatic dissemination requires tumor cells to escape the primary lesion and colonize distant organs, the mechanisms by which primary tumor cells gain metastatic competence remain poorly understood. Increasing evidence demonstrates that fusion of tumor (i....

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Literature Corpus work: 6eadd1f4-43f4-5b57-a096-5e3fa2971a25
DOI: 10.64898/2026.04.12.717781

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