Article

The effects of the citrullinating enzyme, peptidylarginine deiminase, on the activation of T cells

2017-01-01

Abstract excerpt

Rheumatoid arthritis (RA) and periodontitis (PID) are two chronic inflammatory diseases associated with the modification of self-proteins by citrullinating peptidyl arginine deiminase (PAD) enzymes, leading to a loss of tolerance by the immune system. The main goal of this study was to explore the action of PAD enzymemediated citrullination on T cell membrane proteins and gene expression in relation to the T cell...

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Literature Corpus work: 6ea317b2-6ba6-55af-81ce-9264c82c75b9
DOI: 10.48780/publications.aston.ac.uk.00031707

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