A Secreted Bacterial Peptidylarginine Deiminase Can Neutralize Human Innate Immune Defenses

Abstract excerpt

Bacterial pathogens do not only succeed in breaking the barriers that protect humans from infection, but they also manage to evade insults from the human immune system. The importance of the present study resides in the fact that protein citrullination is shown to represent a new bacterial mechanism for immune evasion. In particular, the oral pathogen P. gingivalis employs this mechanism to defuse innate immune...

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