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Article

Peptidylarginine deiminase type 4: identification of a rheumatoid arthritis-susceptible gene.

Trends in molecular medicine - 1 Nov 2003

Yamada Ryo, Suzuki Akari, Chang Xiotian, Yamamoto Kazuhiko

Abstract excerpt

Recent studies using linkage disequilibrium and SNPs uncovered a rheumatoid arthritis (RA)-susceptible haplotype in the gene encoding peptidylarginine deiminase (PADI) type 4. This gene is one of four known PADI genes that encode enzymes to change arginine into citrulline in proteins. Post-translational modifications of proteins, including peptidyl citrullination, are related to autoimmunity, and peptidyl...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14604829
DOI: 10.1016/j.molmed.2003.09.010

Genes

PADI4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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