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<i>Aotus nancymaae</i> model predicts human immune response to the placental malaria vaccine candidate VAR2CSA

2022-06-27

Abstract excerpt

Placental malaria vaccines (PMV) are being developed to prevent severe sequelae of placental malaria (PM) in pregnant women and their offspring. The leading candidate vaccine antigen VAR2CSA mediates parasite binding to placental receptor chondroitin sulfate A (CSA). Despite promising results in small animal studies, recent human trials of the first two PMV candidates (PAMVAC and PRIMVAC) generated limited cross-r...

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Literature Corpus work
6e93a007-7a4d-5038-bf49-445ea496c6b1
DOI
10.1101/2022.06.24.497389
Open publication

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