Article

Predictive Analysis of Binding Affinity among Human Cytomegalovirus (HCMV) Proteins and Class-I Major Histocompatibility Complex (MHC-I) Molecules

2024-12-16

Abstract excerpt

Human Cytomegalovirus (HCMV) is a ubiquitous pathogen that establishes lifelong infections by evading the host immune system, particularly through targeting Class I Major Histocompatibility Complex (MHC-I) molecules. This immune evasion is mediated by a subset of viral proteins, including unique short (US) and unique long (UL) glycoproteins, which disrupt MHC-I antigen presentation and impair cytotoxic T-cell resp...

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Literature Corpus work: 6e8e0277-3444-5099-ab89-6de978ae761e
DOI: 10.20944/preprints202412.1248.v1

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Predictive Analysis of Binding Affinity among Human Cytomegalovirus (HCMV) Proteins and Class-I Major Histocompatibility Complex (MHC-I) MoleculesDOI 10.20944/preprints202412.1248.v1Read

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